Description:Wilms tumor is a rare kidney cancer that is usually diagnosed in children under the age of six. Wilms tumor is mostly the result of aberrations in WT1 gene, located on chromosome 11p13. In addition to being a risk factor for Wilms tumor, WT1 aberrations cause extra renal complications and other malignancies. This book brings together the basic and clinical aspects of Wilms tumor and WT1 research under three sections. Section I provides a comprehensive guide to the epidemiology, diagnostics, management, and treatment of Wilms tumor. Section II covers the biological aspects of Wilms tumor and WT1. Section III focuses on the role of WT1 in cardiac development, prostate cancer, glioblastoma and minimal residual disease.Contributors: 64; Chapters: 16; Figures: 50; Tables: 20; Pages: 294About The Editor: Marry M. van den Heuvel-Eibrink, MD, PhDProfessor Marry M. van den Heuvel-Eibrink, MD, PhD, is a senior consultant in pediatric oncology and hematology at the Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands, where she is responsible for the now established centralized care and translational research program for all children with renal tumors in the Netherlands. She is the current Chair of the European Working Group on Myelodysplastic Syndromes (EWOG-MDS) foundation, and the Dutch Childhood Oncology Group (DCOG) renal tumor committee. She is the co-chair of the International Society of Paediatric Oncology-Renal Tumour Study Group (SIOP-RTSG), steering committee member of the DCOG late effects consortium, and an active member of IBFM-AML study group. From 1997-2014 she was a senior consultant at the Erasmus MC-Sophia Children’s Hospital, Rotterdam. During this period, she was the Working Group leader of the Erasmus MC Postgraduate Molecular Medicine School, which is recognized by the Dutch Royal Academy of Science and Arts. Her major research interest is translational research in pediatric cancer, with a special focus on renal tumors, and the (genetic) variation of early and late childhood cancers. Professor van den Heuvel-Eibrink has published over 260 international peer reviewed manuscripts and is the supervisor of over 25 finalized and ongoing PhD projects.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Wilms Tumor. To get started finding Wilms Tumor, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Description: Wilms tumor is a rare kidney cancer that is usually diagnosed in children under the age of six. Wilms tumor is mostly the result of aberrations in WT1 gene, located on chromosome 11p13. In addition to being a risk factor for Wilms tumor, WT1 aberrations cause extra renal complications and other malignancies. This book brings together the basic and clinical aspects of Wilms tumor and WT1 research under three sections. Section I provides a comprehensive guide to the epidemiology, diagnostics, management, and treatment of Wilms tumor. Section II covers the biological aspects of Wilms tumor and WT1. Section III focuses on the role of WT1 in cardiac development, prostate cancer, glioblastoma and minimal residual disease.Contributors: 64; Chapters: 16; Figures: 50; Tables: 20; Pages: 294About The Editor: Marry M. van den Heuvel-Eibrink, MD, PhDProfessor Marry M. van den Heuvel-Eibrink, MD, PhD, is a senior consultant in pediatric oncology and hematology at the Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands, where she is responsible for the now established centralized care and translational research program for all children with renal tumors in the Netherlands. She is the current Chair of the European Working Group on Myelodysplastic Syndromes (EWOG-MDS) foundation, and the Dutch Childhood Oncology Group (DCOG) renal tumor committee. She is the co-chair of the International Society of Paediatric Oncology-Renal Tumour Study Group (SIOP-RTSG), steering committee member of the DCOG late effects consortium, and an active member of IBFM-AML study group. From 1997-2014 she was a senior consultant at the Erasmus MC-Sophia Children’s Hospital, Rotterdam. During this period, she was the Working Group leader of the Erasmus MC Postgraduate Molecular Medicine School, which is recognized by the Dutch Royal Academy of Science and Arts. Her major research interest is translational research in pediatric cancer, with a special focus on renal tumors, and the (genetic) variation of early and late childhood cancers. Professor van den Heuvel-Eibrink has published over 260 international peer reviewed manuscripts and is the supervisor of over 25 finalized and ongoing PhD projects.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Wilms Tumor. To get started finding Wilms Tumor, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.